The Society of Cosmetic Scientists promotes education, research and collaboration to advance the science of cosmetics

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19 OCTOBER 2017



Venue  Daresbury Sci Tech  
The Innovation Centre, Sci-Tech Daresbury, Keckwick Lane, Daresbury, Cheshire WA4 4FS

Jack Ferguson (Skinnovation)
Carol Treasure (XCellR8)
Richard Bojar (Independent Consultant)
Marie Reynolds (Alba Science)

An opportunity will also be available to tour the XCellR8 lab and to see some in vitro methods in action. You’ll be able to see human cells and reconstructed skin models being used to assess safety and efficacy endpoints such as irritation and anti-oxidant activity, and discuss the practicalities of animal-free cosmetics testing.

Testing for Functionality and Claims Support
Jack Ferguson  Skinnovation
The importance of trial design and the correct parameters to measure and how they are measured is fundamental to demonstrating performance and proving and supporting product claims. The talk will present best practice for claims support of pack and advertising claims and explain the regulatory controls that need to be considered.

Practical Applications of In Vitro Tests to Support Safety and Efficacy Claims
Dr Carol Treasure  Founder, XCellR8
How can in vitro tests provide real, useful data to support safety and efficacy claims for cosmetic products? What’s possible already and what’s on the cards for the future? In vitro technologies are evolving rapidly and can provide powerful, quantifiable evidence for cosmetic claim support, but choosing the optimal in vitro testing strategy – and keeping pace with changing technology – presents a challenge for both formulators and ingredient developers.  We will clarify which tests are currently available to satisfy the regulators and the wider range of options that can be used in product development. We will look at some of the latest exciting advances, and case studies in areas including skin sensitisation, mildness and anti-oxidant activity. The talk will include a realistic look at the current limitations of non-animal testing and how this could be addressed in the future – and asks the question: ‘What is truly animal-free testing?’ 

Studying the Skin/Microbiome Complex using 3D in vitro reconstructed human skin models
Richard Bojar  Independent Consultant
Three-dimensional (3D) human skin models are an accepted part of the testing and regulatory landscape in skin-related industries. There are several established commercial model systems and a multitude of academic, lab-specific 3D in vitro reconstructed human skin models, all with different characteristics, strengths and weaknesses. Some are simple and better suited to applications such as higher throughput screening while others are more sophisticated and capable of complex responses. In all cases the primary objective is to produce a layered cellular structure with functional barrier qualities similar to human skin. However, in no way can it be claimed that these models provide the perfect solution to all the research requirements of skin scientists and their limitations need to be appreciated. Labskin is a commercial 3D in vitro skin model based on the original Leeds Model specifically developed for studying interactions between the skin and its microbiome. The method of construction of Labskin using a fibrin-based dermal matrix rather than collagen provides a robust physical structure, which may also have benefits for use in other testing applications. 

Face the Future
Marie Reynolds  Alba Science


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